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Journal Issue - Volume 159 Issue 4 (February 2010)

EDITORIAL
Anthony P Davenport, Craig Daly
Published online on Feb 23, 2010
DOI: 10.1111/j.1476-5381.2010.00685.x (p 735-737)

Bimolecular fluorescence complementation: lighting up seven transmembrane domain receptor signalling networks
Rachel H Rose, Stephen J Briddon, Nicholas D Holliday
Published online on Dec 10, 2009
DOI: 10.1111/j.1476-5381.2009.00480.x (p 738-750)

Trafficking and signalling of gonadotrophin-releasing hormone receptors: an automated imaging approach
AR Finch, KR Sedgley, SP Armstrong, CJ Caunt, CA McArdle
Published online on Nov 03, 2009
DOI: 10.1111/j.1476-5381.2009.00413.x (p 751-760)

Visualization of gene expression in the live subject using the Na/I symporter as a reporter gene: applications in biotherapy
Patrick Baril, Pilar Martin-Duque, Georges Vassaux
Published online on Oct 08, 2009
DOI: 10.1111/j.1476-5381.2009.00412.x (p 761-771)

Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A₁ receptor ligands
Jillian G Baker, Richard Middleton, Luke Adams, Lauren T May, Stephen J Briddon, Barrie Kellam, Stephen J Hill
Published online on Jan 26, 2010
DOI: 10.1111/j.1476-5381.2009.00488.x (p 772-786)

Fluorescent ligand binding reveals heterogeneous distribution of adrenoceptors and 'cannabinoid-like' receptors in small arteries
CJ Daly, RA Ross, J Whyte, CM Henstridge, AJ Irving, JC McGrath
Published online on Feb 05, 2010
DOI: 10.1111/j.1476-5381.2009.00608.x (p 787-796)

Dynamic monitoring of NET activity in mature murine sympathetic terminals using a fluorescent substrate
Lauren K Parker, Julia A Shanks, James AG Kennard, Keith L Brain
Published online on Feb 05, 2010
DOI: 10.1111/j.1476-5381.2009.00574.x (p 797-807)

Advances in imaging of new targets for pharmacological intervention in stroke: real-time tracking of T-cells in the ischaemic brain
F Ortolano, P Maffia, G Dever, G Rodolico, OR Millington, MG De Simoni, JM Brewer, TJ Bushell, P Garside, HV Carswell
Published online on Dec 10, 2009
DOI: 10.1111/j.1476-5381.2009.00527.x (p 808-811)

Positron emission tomography of [¹⁸F]-big endothelin-1 reveals renal excretion but tissue-specific conversion to [¹⁸F]-endothelin-1 in lung and liver
Peter Johnström, Tim D Fryer, Hugh K Richards, Janet J Maguire, John C Clark, John D Pickard, Anthony P Davenport
Published online on Feb 23, 2010
DOI: 10.1111/j.1476-5381.2010.00641.x (p 812-819)

Lack of effect of the α_2C-adrenoceptor Del322-325 polymorphism on inhibition of cyclic AMP production in HEK293 cells
MD Montgomery, DB Bylund
Published online on Jan 28, 2010
DOI: 10.1111/j.1476-5381.2009.00584.x (p 820-830)

Rimonabant (SR141716) induces metabolism and acquisition of fertilizing ability in human sperm
S Aquila, C Guido, A Santoro, P Gazzerro, C Laezza, MF Baffa, S Andò, M Bifulco
Published online on Jan 08, 2010
DOI: 10.1111/j.1476-5381.2009.00570.x (p 831-841)

Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis
PH Schafer, A Parton, AK Gandhi, L Capone, M Adams, L Wu, JB Bartlett, MA Loveland, A Gilhar, Y-F Cheung, GS Baillie, MD Houslay, H-W Man, GW Muller, DI Stirling
Published online on Dec 24, 2009
DOI: 10.1111/j.1476-5381.2009.00559.x (p 842-855)

Deoxyelephantopin, a novel multifunctional agent, suppresses mammary tumour growth and lung metastasis and doubles survival time in mice
Chi-Chang Huang, Chiu-Ping Lo, Chih-Yang Chiu, Lie-Fen Shyur
Published online on Jan 25, 2010
DOI: 10.1111/j.1476-5381.2009.00581.x (p 856-871)

Bidirectional modulation of isoflurane potency by intrathecal tetrodotoxin and veratridine in rats
Y Zhang, M Guzinski, EI Eger II, MJ Laster, M Sharma, RA Harris, HC Hemmings Jr
Published online on Jan 25, 2010
DOI: 10.1111/j.1476-5381.2009.00583.x (p 872-878)

Functional interactions between 5-HT_2A and presynaptic 5-HT_1A receptor-based responses in mice genetically deficient in the serotonin 5-HT transporter (SERT)
Meredith A Fox, Alison R Stein, Helen T French, Dennis L Murphy
Published online on Jan 27, 2010
DOI: 10.1111/j.1476-5381.2009.00578.x (p 879-887)

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