Angina: New Drug Gets Right to the Heart of the Problem

A compound designed to prevent chest pains in heart patients has shown promising results in animal studies, say scientists. In the second issue of the British Journal of Pharmacology to be published by Wiley-Blackwell, researchers from the Centre de Recherche Pierre Fabre in France, show that the novel compound F15845 has anti-angina activity and can protect heart cells from damage without the unwanted side effects often experienced with other drugs.

RESEARCH PAPER
F 15845 inhibits persistent sodium current in the heart and prevents angina in animal models
B Vacher, C Pignier, R Létienne, Y Verscheure and B Le Grand

COMMENTARY
Persistent (current) in the face of adversity . . . A new class of cardiac anti-ischaemic compounds on the horizon?
David A Saint

To read more, see the full Press release or read the paper by Vacher et al. and the commentary on the paper by Saint for free.