British Journal of Pharmacology

Guide to Receptors and Channels (GRAC)

British Journal of Pharmacology                                                                                                                         
Supplement:
Volume 158, Issue S1 (November 2009)

SPH Alexander, A Mathie, JA Peters

  

 FREE access to the full contents here 

What is the GRAC?
The great proliferation of drug targets in recent years has driven the need to organise and condense the information in a logical way. This is the underlying reason for the Guide to Receptors and Channels (GRAC), distributed with the British Journal of Pharmacology. This authoritative but user-friendly publication allows a rapid overview of the key properties of a wide range of established or potential pharmacological targets. The information is provided succinctly, so that a newcomer to a particular target group can identify the main elements "at a glance".

Targets have been selected for inclusion where there is sufficient pharmacological information to allow clear definition or where, in our view, there is clear interest in this molecular class from the pharmacological community. The underlying philosophy has been to present data on human receptors and to describe agents that represent the most selective available (either by donation or from commercial sources), now or in the near future.

The GRAC is divided into seven sections, which comprise pharmacological targets of similar structure/function. These are:
• 7TM receptors
• LGIC
• ion channels
• nuclear receptors
• catalytic receptors
• transporters
• enzymes

Citing the GRAC
Citations to information in this edition of the GRAC should take the form:
Alexander, S.P.H., Mathie, A., & Peters, J.A. (2009). Guide to Receptors and Channels (GRAC), 4th edition (2009). Br. J. Pharmacol., 158 (Suppl. 1), S1–S254.
 

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